Our Current Studies

Microglial Activation in Alzheimer’s Disease and Mild Cognitive Impairment

Microglial Activation in Alzheimer’s Disease and Mild Cognitive Impairment

What is this study?

The aim of this research study is to evaluate brain changes seen in some Alzheimer’s disease patients (protein build-up in the brain and brain inflammation).

With this study we hope to learn more about the changes that occur in the brain in people with AD and mild cognitive impairment. We hope this information should help us to develop effective preventative treatments in the future.

Who are we looking for?

We are interested in recruiting people with no memory problems (healthy controls), those with mild memory problems (such as mild cognitive impairment) and Alzheimer’s disease patients. Refreshments will be provided and travel costs will be reimbursed.

What the study involves

There are normally between 5-6 appointments, depending how you would like to sandwich the appointments together. We can have some of the appointments on the same day, to make fewer (but longer) visits.

At the beginning of the study, you will have a medical screening and blood test, taking about one hour and a cognitive assessment (taking about 2 hours). In different visits, you will then have an MRI scan (about one hour), a first PET scan appointment (about 3:30 hours), a second PET scan appointment (about 2 hours) and for 8 subjects an optional third PET scan (about 90 minutes). You will have medical assessment before and after the scans, and the day after.

All visits take place at the Hammersmith Hospital.

What to do if I am interested

For more information about this study, please contact:
The Memory Team Email:
Telephone: 0208 383 3704 or 0208 383 1969 or 0208 383 4850.