Imperial College Memory Research Centre

Welcome to our Memory Centre

Take Part in a Study

We are looking for people with mild memory problems, Alzheimer¹s disease, and healthy volunteers.

If you are interested in taking part, please contact us by using our e-mail: memory@imperial.ac.uk or by telephone 0208 383 3704 or by sending us a message by using the contact us form.

Apply Online

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Imperial College Memory Research Centre

Paul Edison

At the Imperial College Memory Research Centre led by Dr Paul Edison, we focus our research on memory impairment in Alzheimer's disease, mild cognitive impairment and other causes of dementia, and the treatment for these conditions.

Dr Edison is a Clinical Senior Lecturer in the Division of Brain Sciences at Imperial College London and a visiting Professor at Cardiff University, Wales. He is also a Consultant Physician at Hammersmith Hospital, London.

Dr Edison’s research has focused on neuroimaging with novel molecular probes using PET and magnetic resonance techniques for imaging pathophysiological changes associated with Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative diseases. He has extensive experience in PET imaging in different neurodegenerative and neuroinflammatory conditions. Combined with his clinical expertise in different types of degenerative diseases and dementia, he has investigated the relationship between amyloid deposition, microglial activation, and glucose metabolism in various disorders, along with evaluating different transporters in the brain. His work in assessing microglial activation and amyloid load showed that both of these are increased in Alzheimer’s disease, and that microglial activation correlates with cognition, while amyloid load does not correlate with cognition. He was an MRC Clinical Research Fellow before he became a HEFCE Clinical Senior Lecturer.

His work now focuses on neuroinflammation and the interplay between inflammation and immunity in neurodegenerative and neuroinflammatory disease, and relating these with genetic information. He is also evaluating methods of modulating inflammation and amyloid in Alzheimer’s disease, and the influence of cardiometabolic factors on the development of neurodegenerative diseases by means of clinical and preclinical studies.

He leads the Imperial College Memory Research Centre, and is the Chief Investigator of several imaging studies using PET and MRI, and heads multicentre studies evaluating novel treatment of Alzheimer's and other neurodegenerative diseases. He also runs a memory clinic at Imperial College Healthcare NHS Trust.

Our Current Studies

Evaluating Liraglutide (diabetes drug) in Patients with Alzheimer's Disease

Evaluating Liraglutide (diabetes drug) in Patients with Alzheimer's Disease

A phase II trial evaluating the treatment of the diabetic medication, Liraglutide, as a potential new treatment for patients with mild to moderate Alzheimer’s disease.

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Neuro inflammation and Amyloid Study

Neuro inflammation and Amyloid Study

Investigating the relationship between inflammation and amyloid in the brains of patients with mild cognitive impairment and Alzheimer’s disease.

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Microglial Activation in Alzheimer’s Disease and Mild Cognitive Impairment

Microglial Activation in Alzheimer’s Disease and Mild Cognitive Impairment

Investigating the relationship between inflammation and amyloid in the brains of patients with mild cognitive impairment and Alzheimer’s disease using a novel tracer.

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Astroglial Activation, β-amyloid Deposition and Neuronal Activity in AD

Astroglial Activation, β-amyloid Deposition and Neuronal Activity in AD

Investigating the relationship between astroglia and amyloid in the brains of people with Alzheimer’s disease and mild cognitive impairment, and how this affects thinking and memory using a novel astroglial activation imaging marker.

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Surgery and Neuroinflammation

Surgery and Neuroinflammation

A study looking at the relationship between inflammation in the brain and obesity in patient’s undergoing gastric bypass surgery. This study involves a PET and MRI scan prior to the surgery, and then again 6 months after the surgery.

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Uptake and Kinetics of [18F]ICMT11

Uptake and Kinetics of [18F]ICMT11

Evaluating brain changes seen in some Alzheimer’s disease patients (protein build-up and specific proteins activity in the brain).

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Take part in a study

We are looking for people with mild memory problems, Alzheimer’s disease, and healthy volunteers.

If you are interested in taking part, please contact us by using our e-mail: memory@imperial.ac.uk or by telephone 0208 383 3704 or by sending us a message by using the contact us form.

Please include your age, name and contact details and a brief description of the enquiry / study.

Apply Online

Have a question? ...Please check our “Frequently Asked Questions

OUR LATEST NEWS

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Suspected non-Alzheimer's pathology – Is it non-Alzheimer’s or non-amyloid?

This article looks into progressive loss of neurons in the brain, which is one of the main processes in dementia and age-related cognitive impairment. This can be detected with current biomarker tests.

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Open label extension for the ELAD study

An exciting new stage is iminent for the patients who wish to continue after completing the ELAD trial of the anti-diabetic drug, liraglutide, in patients with Alzheimer’s disease.

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Neuroinflammation in Alzheimer’s disease Current evidence and future directions

Several trials have investigated the use of anti-amyloid therapies in Alzheimer’s disease, but these have all had disappointing results.

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